Bag-3 Polyclonal Antibody
简要描述:Bag-3 Polyclonal Antibody宿主: Polyclonal, Rabbit,IgG反应性: Human;Rat;Mouse;应用: WB;IHC;IF;ELISAWB:蛋白质印迹法 IHC-P:石蜡切片样本的免疫组织化学法 IHC-F:冰冻切片样本的免疫组织化学法 ICC/IF:免疫细胞荧光 IP:免疫沉淀法 FC:流式细胞术 ELISA:酶联免疫吸附测定
产品型号: YP-Ab-00580
所属分类:多克隆抗体
更新时间:2024-10-31
详细说明:
Bag-3 Polyclonal Antibody
抗体,也叫免疫球蛋白(Ig),是一种能特异性结合抗原的糖蛋白,而抗原是在易感染动物体内引发抗体产生的物质。在体内,抗体是由于外源性分子的侵袭而产生的。抗体以一个或者多个Y字形单体存在,每个Y字形单体由4条多肽链组成,包含两条相同的重链和两条相同的轻链。轻链和重链是根据它们的分子量大小来命名的。Y字形结构的顶端是可变区,为抗原结合部位。任何一个抗体的轻链都可以分为κ或λ型(基于小分子多肽结构上的差异),每一个抗体的重链则决定了它的类或型。
产品详情
Bag-3 Polyclonal Antibody detects endogenous levels of Bag-3 protein.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from the Internal region of human BAG3. AA range:311-360
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008].
天津俊达生物科技有限公司,是从事实验室耗材销售的现代化生物科技企业,公司本着“诚信为本,互利共赢"的核心价值观,秉承“以市场为导向,提供服务"的宗旨为各大院校、科研单位、第三方实验室检测机构等提供的产品和服务。目前公司主要经营分子生物学、细胞生物学、免疫学等生物学产品,多种实验室耗材 欢迎垂询!
备注:图片仅供参考。仅供科研,不可用于临床。