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TWEAK Polyclonal Antibody

TWEAK Polyclonal Antibody

简要描述:TWEAK Polyclonal Antibody
宿主: Polyclonal, Rabbit,IgG
反应性: Human;Mouse
应用: WB;IHC;IF;ELISA

产品型号: YP-Ab-00546

所属分类:多克隆抗体

更新时间:2024-11-01

详细说明:

TWEAK Polyclonal Antibody

抗体,也叫免疫球蛋白(Ig),是一种能特异性结合抗原的糖蛋白,而抗原是在易感染动物体内引发抗体产生的物质。在体内,抗体是由于外源性分子的侵袭而产生的。抗体以一个或者多个Y字形单体存在,每个Y字形单体由4条多肽链组成,包含两条相同的重链和两条相同的轻链。轻链和重链是根据它们的分子量大小来命名的。Y字形结构的顶端是可变区,为抗原结合部位。任何一个抗体的轻链都可以分为κ或λ型(基于小分子多肽结构上的差异),每一个抗体的重链则决定了它的类或型。

产品详情
TWEAK Polyclonal Antibody detects endogenous levels of TWEAK protein.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human TNFSF12. AA range:41-90
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]


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备注:图片仅供参考。仅供科研,不可用于临床。




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