Rad50 Polyclonal Antibody
简要描述：Rad50 Polyclonal Antibody宿主: Polyclonal, Rabbit,IgG反应性: Human;Mouse;Rat应用: WB;IHC;IF;ELISA
产品型号： YP-Ab-00509
所属分类：多克隆抗体
更新时间：2024-11-01
详细说明：
Rad50 Polyclonal Antibody
抗体，也叫免疫球蛋白（Ig），是一种能特异性结合抗原的糖蛋白，而抗原是在易感染动物体内引发抗体产生的物质。在体内，抗体是由于外源性分子的侵袭而产生的。抗体以一个或者多个Y字形单体存在，每个Y字形单体由4条多肽链组成，包含两条相同的重链和两条相同的轻链。轻链和重链是根据它们的分子量大小来命名的。Y字形结构的顶端是可变区，为抗原结合部位。任何一个抗体的轻链都可以分为κ或λ型（基于小分子多肽结构上的差异），每一个抗体的重链则决定了它的类或型。
产品详情
Rad50 Polyclonal Antibody detects endogenous levels of Rad50 protein.
免疫原详细信息
The antiserum was produced against synthesized peptide derived from human RAD50. AA range:681-730
相关试剂
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
RAD50 double strand break repair protein(RAD50) Homo sapiens The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
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备注：图片仅供参考。仅供科研，不可用于临床。
Rad51D Polyclonal Antibody
